Forced Diuretic, Cedilanid
Sediaan Lasix (Furosemide); 20 mg/ 2 cc ampul
Cara 12,5 amp lasix (250 mg) dalam 200 cc Dextros 5% habis dalam 1/2- 1jam (133 gtt/menit)
From: onlinesmedicines
Cedinalid Bolus
Sediaan a. Deslanoside 400 ugr/ 2 cc (ampul)
b. lanatosid C 250 ugr (tablet salut)
dari: MinClinic
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Mechanism Of Action: Cedilanid-d inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations of calcium may promote activation of contractile proteins (e.g., actin, myosin). Cedilanid-d also acts on the electrical activity of the heart, increasing the slope of phase 4 depolarization, shortening the action potential duration, and decreasing the maximal diastolic potential.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Deslanoside
Synonyms: Not Available
Drug Category: Anti-Arrhythmia Agents; Cardiotonic Agents; Enzyme Inhibitors
Drug Type: Small Molecule; Approved
Other Brand Names containing Deslanoside: Cedilanid-d; Deacetyllanatoside C;
Absorption: Little absorption from the gastrointestinal tract (40%).
Toxicity (Overdose): Symptoms of overdose include ventricular tachycardia, ventricular fibrillation, progressive bradyarrhythmias, or heart block.
Protein Binding: 20%
Biotransformation: Not Available
Half Life: 36 hours
Dosage Forms of Cedilanid-d: Not Available
Chemical IUPAC Name: 4-[(3S,5R,8R,9R,10S,12R,13S,14S,17R)-12,14-dihydroxy-3-[(2R,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5H-furan-2-one
Chemical Formula: C47H74O19
Deslanoside on Wikipedia: http://en.wikipedia.org/wiki/Deslanoside
Organisms Affected: Humans and other mammals
CARA
1 ampul diencerkan dengan dextrose 5% sampai 10 cc --> bolus iv pelan2 (10')
Indikasi: Decomp cordis dengan HR > 120 x/menit (Fibrilasi)
Lanoxi: Digoxin
Cara 12,5 amp lasix (250 mg) dalam 200 cc Dextros 5% habis dalam 1/2- 1jam (133 gtt/menit)
From: onlinesmedicines
Cedinalid Bolus
Sediaan a. Deslanoside 400 ugr/ 2 cc (ampul)
b. lanatosid C 250 ugr (tablet salut)
 |
| Deslanoside https://xudonghaipu.en.ecplaza.net/products/deslanoside-injection_1315996 |
Cedilanid-d - General Information
dari: MinClinic
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.Pharmacology of Cedilanid-d
Cedilanid-d is a cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.Additional information about Cedilanid-d
Cedilanid-d Indication: For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.Mechanism Of Action: Cedilanid-d inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations of calcium may promote activation of contractile proteins (e.g., actin, myosin). Cedilanid-d also acts on the electrical activity of the heart, increasing the slope of phase 4 depolarization, shortening the action potential duration, and decreasing the maximal diastolic potential.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Deslanoside
Synonyms: Not Available
Drug Category: Anti-Arrhythmia Agents; Cardiotonic Agents; Enzyme Inhibitors
Drug Type: Small Molecule; Approved
Other Brand Names containing Deslanoside: Cedilanid-d; Deacetyllanatoside C;
Absorption: Little absorption from the gastrointestinal tract (40%).
Toxicity (Overdose): Symptoms of overdose include ventricular tachycardia, ventricular fibrillation, progressive bradyarrhythmias, or heart block.
Protein Binding: 20%
Biotransformation: Not Available
Half Life: 36 hours
Dosage Forms of Cedilanid-d: Not Available
Chemical IUPAC Name: 4-[(3S,5R,8R,9R,10S,12R,13S,14S,17R)-12,14-dihydroxy-3-[(2R,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5H-furan-2-one
Chemical Formula: C47H74O19
Deslanoside on Wikipedia: http://en.wikipedia.org/wiki/Deslanoside
Organisms Affected: Humans and other mammals
CARA
1 ampul diencerkan dengan dextrose 5% sampai 10 cc --> bolus iv pelan2 (10')
Indikasi: Decomp cordis dengan HR > 120 x/menit (Fibrilasi)
Lanoxi: Digoxin
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